Ngaphambi kokukhululwa kwe-Fallout 76, kusasele izinyanga ezinhlanu cishe, kodwa wonke umuntu angakwazi ukulungiselela imithwalo nemithwalo yemodi yokudlala imodi yabadlali abaningi. Ukuguqulwa kwe-Fallout 4, eyakhiwe ngumsebenzisi ngaphansi kwesiteketiso SKK50, yenzelwe ukubuyisa izici eziyinhloko zephrojekthi entsha ye-Bethesda ku-injini endala.
Ngokwefashini, okuthiwa i-Fallout 4-76, abadlali ngeke babone iningi le-NPC. Esikhundleni salokho, lo mdlalo uzokhukhulwa nalabo okuthiwa yi-griffers, okuba, ngokulingisa abanye abadlali, bazohlambalaza bese bezama ukubulala umlingisi oyinhloko. I-adrenaline eyengeziwe egazini lalabo abaye banquma ukuzwa ukuwela ku-4-76 kuzokwandisa ikhono lokufa nganoma yisiphi isikhathi kusukela ebhomu le-athomu eliqhume eduze.
Ukuwa kwe-76 kuyinto umdlalo wokudlala indima yabadlali abaningi, lapho, ngokungafani nezingxenye zangaphambilini zochungechunge, ngeke kube ne-NPC elawulwa yi-computer. Abantu abavela ku-24 kuya ku-32 bazokwazi ukudlala ngesikhathi esisodwa kwikhadi elilodwa, futhi izici eziyinhloko zephrojekthi zizofaka ikhono lokusebenzisa izikhali zenuzi. Ukukhishwa kwe-Fallout 76 kuhlelwe ngoNovemba 14, 2018.